Scientific Program

Conference Series LLC Ltd invites all the participants across the globe to attend 10th International Conference on Clinical and Medical Case Reports
Toronto | Ontario | Canada.

Day 1 :

Keynote Forum

Adrian Baranchuk MD FACC FRCPC

Queen`s University, Canada

Keynote: Case Reports contribute to knowledge translation

Time : 09:00-09:30

Case Reports 2018 International Conference Keynote Speaker Adrian Baranchuk MD FACC FRCPC photo
Biography:

Dr. Adrian Baranchuk, a native of Buenos Aires, Argentina, obtained his MD from the University of Buenos Aires in 1990. After qualifying in Internal Medicine and Cardiology at Sanatorio Mitre, Buenos Aires (1995), he completed a Clinical Fellowship in Cardiac Electrophysiology at the same institution under the supervision of Dr. Claudio Muratore. 

He completed his Clinical Fellowship (1997) and joined the Arrhythmia Service until 2002 when he immigrated to Spain to join the Arrhythmia Service at the Fundacion Jimenez Diaz; working as a Research Fellow in the Animal Lab under the supervision of Dr. Jeronimo Farre. For his work in this lab, he was awarded with the 3rd Chinchona Award (Sponsored by 3M Foundation). During his stay in Madrid, Spain, he received a grant (as PI) from MAPFRE MEDICINA Foundation (Madrid, Spain). (Ultrasonic Analysis of Radiofrequency Lesion of the Pulmonary Venous Wall through Three-dimensional Intravascular Echography: Therapeutical Implications for Atrial Fibrillation Ablation).

Dr. Baranchuk was appointed as a Clinical Fellow in Electrophysiology at McMasterUniversity in September 2003, under the supervision of Drs. Carlos Morillo and Stuart Connolly. In 2004, he won the 1st Prize at the Fellows Forum, “5th Annual EP Fellows Course” (Sponsored by Medtronic) held in Montebello.

Dr. Baranchuk was appointed as an Assistant Professor of Medicine at Queen’s University to join the Division of Cardiology in June 2006. He is an active member of the Arrhythmia Service and has founded the EP Training Program in 2007. Currently the program has 3 Clinical Fellows.

In 2009 he received his cross-appointment with the Department of Physiology and Biomolecular Sciences.

His scholarly activity work includes sleep apnea and cardiovascular disease, specifically the link between sleep apnea and cardiac arrhythmias, complex ablation, cardiac devices and Electrophysiology and Electrocardiology education. He is a member of numerous editorial boards and reviewer of several journals. The recipient of a teaching award (Outstanding Contribution in the Core Internal Medicine Program) and nominated in 2009, 2010 & 2012 for teaching awards from the Faculty of Health Sciences. He is a member of the Mentorship Program at Queen’s University.

Dr. Baranchuk has been very active presenting his work at national and international meetings. In the last 4 years, he visited Argentina, Chile, Colombia, Venezuela, Russia, Brazil, Poland, Germany, Spain, USA; and several places in Canada.

His first book, Atlas of Advanced ECG Interpretation, has been recently released (REMEDICA, UK) and represents a big collaboration effort from well-recognized electrophysiologists of all around the world.

He has published more than 200 articles in well-recognized international journals, 20 book chapters and presented more than 150 abstracts all around the world.

He was promoted to the rank of Associate Professor of Medicine and Physiology in 2010.

Abstract:

Will be updated shortly

Case Reports 2018 International Conference Keynote Speaker Matthew B. Carroll, MD, FACP, FACR photo
Biography:

Matthew B. Carroll is a board certified Rheumatologist who is clinically active and currently employed by the Singing River Health System.  He has had a passion for clinical research and has been an active member of the growing research team at his community hospital.  He retired from the United States Air Force in 2017 but during his active duty service developed over 15 protocols and has published over 20 articles.  A recent passion has been exploring the possible beneficial role of IL-6 blockade on acute myocardial infarction.  He launched an ambitious protocol studying the short term effects on major adverse cardiac events which though it was eventually ended after futility analysis suggested no benefit, did enroll over 20 subjects and provided 180 day follow-up of data collection.  He continues to actively lobby the study of IL-6 blockade in other areas of Cardiology.

Abstract:

Statement of the Problem: Tocilizumab (TCZ) is an important biologic response modifier that Rheumatologists routinely employ in the treatment of several systemic autoimmune diseases. TCZ binds to interleukin (IL)-6 receptors, inhibits cellular activation, and mitigates inflammation by IL-6. In mid-2017 TCZ was approved by the U.S. Food and Drug Administration for its first non-rheumatologic condition, the treatment of chimeric antigen receptor (CAR) T cell-induced severe or life-threatening cytokine release syndrome in patients 2 years of age or older. With this approval and with the increasing use of TCZ off-label for other nonrheumatologic conditions such as Castleman’s Disease and its variant TAFRO syndrome, where else might TCZ be successfully utilized as treatment? Recently interesting data has been published regarding possible use of TCZ in the treatment of myocardial infarction.  This review will focus on the role of IL-6 and it’s receptor in myocardial inflammation and association with adverse clinical outcomes. Discussed are results from one animal study and two human trials have been published that studied the effect of TCZ in patients with acute myocardial infarction. Finally, this review summarizes the current data and makes recommendations for future clinical trial development in what hopefully will be a promising application of TCZ for a serious non-rheumatologic condition.

Case Reports 2018 International Conference Keynote Speaker Jennifer L. Doherty-Restrepo, PhD, LAT, ATC photo
Biography:

Jennifer Doherty-Restrepo is a Clinical Associate Professor and Chair of the Department of Athletic Training in the Nicole Wertheim College of Nursing and Health Sciences at Florida International University. Her areas of expertise include andragogy, simulation-based instruction, and professional as well as continuing education in athletic training. Jennifer serves the Athletic Training Profession as a manuscript reviewer for the Journal of Athletic Training and the Athletic Training Education Journal. She is an Associate Editor for the Athletic Training Education Journal. Jennifer serves the Commission on Accreditation of Athletic Training Education as a site visitor. Additionally, she is the Chair of the University and College Athletic Training Student Committee of the Athletic Trainers’ Association of Florida. In recognition of her service and contributions to athletic training education, Jennifer was the recipient of the 2015 Athletic Trainers’ Association of Florida University and College Athletic Trainer of the Year award.

Abstract:

Context: The need for increased screening to detect cardiac diseases in preparticipation physical examinations is a focus in athletic training. Objective: To examine if a simulation-based training can increase athletic training students’ self-reported confidence and clinical competence in conducting a cardiovascular screening. Design: Pretest-posttest design. Participants: 25 first-year athletic training students. Intervention(s): Standardized cardiovascular curriculum. Main Outcome Measure(s): Learner self-reported confidence scale, multiple-choice knowledge exam, and objective structured clinical examination (OSCE) of cardiovascular assessment skills and auditory recognition of heart murmurs. Results: Self-reported confidence increased significantly from 4.4±2.1 to 9.2±3.0 post-intervention (F = 78.7, p < 0.001) with a moderately high effect size (h2=0.789). Knowledge exam scores increased significantly from 11.0±2.5 to 13.6±4.0 post-intervention (F= 5.3, p= 0.031) with a low effect size (h2=0.191). The history-taking assessment of the OSCE increased significantly from 2.6±1.6 to 5.7±1.7 post-intervention (F= 70.1, p< 0.001) with a moderately high effect size (h2=0.751). The clinical skills assessment of the OSCE increased significantly from 4.1±2.8 to 15.6±1.6 post-intervention (F= 415.4, p< 0.001) with a high effect size (h2=0.952). Conclusions: Simulation-based training is an effective tool for increasing students’ self-reported confidence and competence in conducting a cardiovascular screening.

Keynote Forum

Denis Larrivee

Loyola University Chicago, USA

Keynote: Contemplative revelations: Higher faculties in global nervous system integration

Time : 10:30-11:00

Case Reports 2018 International Conference Keynote Speaker Denis Larrivee photo
Biography:

Dr. Denis Larrivee is a Visiting Scholar at Loyola University Chicago and has held professorships at the Weill Cornell University Medical College in New York City and Purdue University, West Lafayette, Indiana. A former fellow at Yale University's Medical School and Department of Biology he received the Association for Research in Vision and Opthalmology's first place award for studies on photoreceptor degenerative and developmental mechanisms. He is the current editor of a text entitled Brain Computer Interfacing and Brain Dynamics with InTech Publishing and an editorial board member of the journals Annals of Neurology and Neurological Sciences (USA) and EC Neurology (UK). An International Neuroethics Society Expert he is the author of more than 50 papers and book chapters in such varied journals/venues as Neurology and Neurological Sciences (USA), EC Neurology (UK), Journal of Neuroscience, Journal of Religion and Mental Health, and IEEE Explore.

Abstract:

Contemplative meditation reveals a latent capacity for personal integration that enhances mental and physical heath through relational and transcendent ordering. Studies of a related meditative practice, mindfulness, reveal, for example, not only positive phenomenological benefits but also substantive physical changes in underlying neural and bodily factors, which are correlated with the duration and frequency of meditative practice. The extended intentional focus of contemplative meditation acquired from the Christian legacy, and then evolved in its later development, implicates an even greater breadth of neural deployment that assists personal integration. They suggest, thereby, a scope of disciplinary consolidation that exceeds that of mindfulness and so likely activates a broader and corresponding range of integrative processes that are latent for implementation as needed. The role played by the brain and nervous system in the self integration of higher faculties, however, is neglected in current philosophy of science models that guide empirical neuroscientific praxis; these latter, rather, are premised on the brain's mediation of coherent and coordinative operation instead of the systemically mediated, mutually constraining influences of peripheral and central neural networks. Indeed, results from contemplative meditation suggest that body and brain are unified through their ordering to higher systemic and ontological ends. Bodily performance in and through intentional actions, for example, shapes the brain and body's neural architecture to yield an integral performance unit. In like manner, higher faculties, like personal identity and intention, emerge from the extended peripheral network throughout the body to unify the whole individual in actions, such as those promoted in contemplative meditation. This paper will pursue an evidence based presentation, discussing the underlying neural events through which self autonomous actions promote and assist personal integration.

Keynote Forum

Amir S Lotfi, MD, FRCPC, FSCAI

Tufts University School of Medicine, USA

Keynote: The distal left radial artery access for coronary angiography and intervention: A new era

Time : 11:00-11:30

Case Reports 2018 International Conference Keynote Speaker Amir S Lotfi, MD, FRCPC, FSCAI photo
Biography:

Amir Lotfi is an associate professor of medicine, Tufts University School of medicine in the cardiology division at Baystate Medical Center.  His training in coronary, carotid and peripheral interventions.  His area of interest includes radial intervention, coronary physiology, coronary imaging, and ischemic preconditioning.

Abstract:

Statement of the Problem:

Patients' intra and post procedural comfort, quick recovery, as well as procedure success, are key elements for choosing the right arterial access site. Radial artery access has been of increasing interest since it was first described. Advanced treatments of coronary lesions, from primary percutaneous interventions during ST elevation myocardial infarction cases to chronic total occlusion cases, have been increasingly done through the radial access. Distal left trans radial artery (dlTRA) is a new technique first described by Kiemineij. We report the first documented US experience of the left distal radial artery access for coronary angiography and interventions.

Methodology & Theoretical Orientation:

dlTRA was attempted on 22 consecutive patients, consented for a cardiac catheterization. 7 patients underwent percutaneous coronary intervention. The left hand is prepped in the usual fashion, exposing the anatomical snuff box. Under ultrasound guidance, the artery is punctured and the sheath is inserted carefully. The cardiac catheterization is completed using standard diagnostic and guiding catheters that are typically chosen for femoral artery access. Haemostasis was achieved with a radial band. Patients had the ability to use the right hand as well as bend their left wrist post procedure.

Conclusion & Significance:

dlTRA was successful in all 22 patients. 7 patients underwent PCI through this approach. Two patients required a multi vessel complex PCI with multiple stents and additional equipment. There were no conversions to the right radial or femoral approach. All patients had excellent haemostasis with a radial band, with no complications. Pre discharge radial pulses were intact in the wrist as well as in the anatomical snuff box. Distal left trans radial access is feasible and safe in patients that are carefully selected and are deemed good candidates. There is a learning curve for developing such program, as is the case with conventional radial access.