Clinical and Medical Case Reports

Biography:

Dr. Pon Ramya Gokul has completed her pediatric post-grad trainee with rotatory postings with 6 months each in NICU and PICU , and several speciality postings. She is currently working as a senior resident at a hospital in Chennai, India.The main responsibilities of evaluating patients, attending rounds , documentation and doing procedures was completed by her sincere efforts. She's sincere in her work and completes her tasks promptly. Also has good communication skills and involves in counseling sessions. She is an ardent learner and is keen on doing procedures. She is compassionate towards sick babies and records clinical notes in a meticulous manner. She has always been greatly interested in research work and publishing articles.

Abstract:

We report a case of calla positive pre B cell acute lymphoblastic leukemia in a 5yr old male child , presented with bilateral proptosis. This is a case report and literature review. A 5 year old male child presented with acute issues of fever with bilateral excruciating knee pain preceding fall, history of bilateral proptosis for 3 months .Initial workup of hemogram, ophthalmology and thyroid evaluation, imaging (MRI &CT orbit ) were normal . Repeat hemogram showed pancytopenia picture with multiple osteolytic lesions in x ray knee, no lymphadenopathy or organomegaly noted. Repeated detailed evaluation done was normal.Following which bone marrow aspiration study was done. Bone marrow studies revealed hypercellular marrow with 40% blasts and flow cytometry results of blasts positive for CD19,CD10 , cCD79a HLADR, confirmed the diagnosis of CALLA POSITIVE PRE B- CELL ACUTE LYMPHOBLASTIC LEUKEMIA (ALL).Proptosis is usually associated with acute myelogenous leukemia , and rare in ALL especially when they precede the systemic disease and should be borne in mind when evaluating for proptosis .